The old bone tissue. Over the time, the bones can become fragile and misshapen. Paget’s disease of bone most commonly occurs in the pelvis, skull, spine and legs.

The risk of bone disease. Your risk also increases. Complications of nerves in your spine.

Bisphosphonates – the medications also used to strengthen bones weakened by osteoporosis – are the mainstay of treatment. For patients who have complications, surgery may be necessary.


Most people who have no bone disease. When symptoms occur, the most common complaint is bone pain.

It is a condition that makes it possible to make it possible to make it possible for the body to generate a bone.

It might be widespread. Your signs and symptoms, if any, will depend on your body.

Pelvis. Can cause hip pain.

Skull. Anxiety can cause hearing loss or headaches.

Spine. If your spine is affected, nerve roots can become compressed. This can cause pain, tingling and numbness in an arm or leg.

Leg. As the bones weaken, they may be bend – causing you to become bowlegged. There can be extra stress on your knees or hip.

Talk to your doctor if you have:

  • Pain in your bones and joints
  • Tingling and weakness in an extremity
  • Bone deformities
  • Unexplained hearing loss, especially if only on one side


Bone is unknown. Scientists suspect a combination of environmental and genetic factors contribute to the disease. Several genes appear to be linked to getting the disease.

It is a controversial.

Risk factors

Factors of bone include:

  • Age. People older than 40 are most likely to develop.
  • Sex. Men are more commonly affected than are women.
  • National origin. England, Scotland, central Europe and Greece. It’s uncommon in Scandinavia and Asia.
  • Family history. If you have a disease, you’re more likely to develop the condition.


In most cases, Paget’s disease of bone progresses slowly. The disease can be managed effectively in nearly all people. Possible complications include:

  • Fractures and deformities. Affected bones break more easily. Bleachers for more than 2 days during the repair of surgeries. Leg bones can bow, which can affect your ability to walk.
  • Osteoarthritis. Misshapen bones can increase the amount of stress on nearby joints, which can cause osteoarthritis.
  • Neurologic problems. There is a problem where the nerves pass through the bone, such as the spine and the skull;
  • Heart failure. It is possible to make it possible for your body to. Sometimes, this increased workload can lead to heart failure.
  • Bone cancer. Bone cancer occurs in about 1 percent of people with Paget’s disease of bone.